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For decades scientists have been warning of a global pandemic, and the COVID-19 coronavirus outbreak has realised their worst fears. COVID-19 and monkeypox make this an essential guide to the future. It narrates a disquieting journey through the history, science, and politics of humankind’s ongoing war against contagion; investigates modern responses; and assesses the chances of eradicating disease in the future. it also reveals how globalisation, mobile populations, climate change, vaccine hesitancy, and drug-resistant pathogens have combined to create the perfect conditions for pandemics to spread.